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Physicians have long noticed wide disparities in the pain tolerance of the people they treat. Among patients with the same condition, pain ratings typically range from “no pain” to “the worst pain imaginable.”
And although some disorders are more painful than others, the variation in distress among individuals with the same physical malady is far greater than the difference in the discomfort people feel, on average, from one condition to the next. “Two soldiers may be shot in the same nerve,” says Stephen G. Waxman, a neurologist at Yale University and the Veterans Administration Connecticut Health Care Center. “One has sensory loss but is otherwise okay; the other has intractable burning pain.”
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One reason pain is so difficult not only to experience but also to talk about is that scientists still don’t fully understand how the body perceives and regulates it.
That picture has become slightly clearer in recent years, largely thanks to the 2021 Nobel Prize-winning discovery of temperature and pressure receptors in the skin that trigger the neurological signals we recognize as acute pain.
Chronic pain, however, has always been more complicated. The links it shares with conditions such as mental health disorders suggest that its origins are far more complex than previously thought.
#7

Since it’s pretty much impossible to go through life without experiencing pain, you might feel unlucky if even minor injuries or discomfort seem to hit you particularly hard. But science suggests that exercise can help increase your pain tolerance.
Using data from a large Norwegian population study of 10,732 adults, researchers at the University Hospital of North Norway in Tromsø analyzed participants’ self-reported activity levels and pain tolerance, which was measured by having them submerge their hands in ice water and rate their pain. The respondents were surveyed twice, roughly eight years apart.
The researchers found that people with more active lifestyles tended to have higher pain tolerance. What’s more, the more participants reported exercising over the course of the study, the greater their capacity for enduring pain became. When both survey periods were considered, those who had increased their physical activity during the interim years also reported higher pain tolerance over time.
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I'd say its top of the totem. Then there's tooth aches.
Edit: Omg friends, I empathize with all of you. And I want to shared some supplements that have helped after my gallbladder removal over 2 decades ago.
I dont take them all daily but these are in my rotation monthly. And of course lots of water. Hope this helps
1. Oxbile
2. Digestive Enzymes
3. Calm magnesium powder
4. Colon cleanses (I go every few months).
#11

It all culminated one night when I awoke one night unable to move. Not because I was paralysed or anything but because every slight movement sent white hot pain through my body. It was terrifying, and seeing my mother sit by my bed helpless was also terrifying. Childhood memories can be spotty, but this was seared into my brain so vividly.
She didn’t ring an ambulance and I think it’s because the doctor had her so messed up. In the morning the pain had dimmed enough that she could carry me to the car and to the hospital.
The next few weeks in hospital that same doctor boasted to his students about this rare find.
#12

It’s a pretty rare reaction to a sunburn. The parts I remember are the worst experiences of my life from both a physical and mental state. And I understand how ridiculous that sounds. lol. My wife refuses to acknowledge it as a real thing and calls it “Satan’s Scratch.” It’s a bit of an ongoing gag with us. The sunburn itself wasn’t even that bad; I’ve certainly had way worse but when I took a shower my entire body lit up.
It basically felt like what I imagine being covered in fire ants feels like. I spent the worst of it in my basement scream crying. I woke up in a puddle of sweat, naked on the cement of my basement floor. I was delusional and lost chunks of time where I’m assuming my brain just shut down from the constant agony. Meanwhile I’m questioning my sanity because all of that is coming from “just a sun burn.” Looking back on it, it almost feels like a fever dream. Which is a little ironic because I was definitely struggling to regulate my body temp.
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my cycling vomiting syndrom is a close second tho lmao.
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